The district of Kameiros stretches along the northwest coast of the island close to the Cape of Ayios Minas (ancient Mylantion) in the foothills of Mt Akramytis. In prehistoric times the Mylantian gods, who taught mankind milling and kneading, were worshipped here. Mycenaean necropoleis have been excavated at Kalamvarda, west of Kameiros.
Finds from the Geometric period (8th c. BC) testify to the existence of a temple dedicated to Athena on the Acropolis. The earthquake of 226 BC destroyed the Classical city and probably the Classical temple of Athena Kameiras.